1559 CE
Queen Catherine de Medicis is said to have popularized the use of tobacco as a headache remedy.

Jean Nicot, a French diplomat and scholar, sent tobacco (as a medicine) to Queen Catherine de Medici. She is said to have popularized the use of tobacco as a remedy against headaches.

Source: Austin, G. A. et al. (1979). Perspectives on the history of psychoactive substance use. NIDA.

Drugs: Tobacco
Regions: France
Topics: Medicinal use of drugs