1999 CE
An improved synthesis method for psilocybin is published

In 1999, David E. Nichols and Stewart Frescas publish an article where they discuss an improved procedure to synthesize psilocybin. The reported method utilizes reaction between the O-lithium salt of 5 and tetra-Obenzylpyrophosphate.

Source: Nichols, D. E. (1999). Improvements to the synthesis of psilocybin. Synthesis.

Drugs: Psilocybin (mushrooms)
Regions: USA (United States of America)