1874 CE
Heroin is synthesized for the first time

Heroin is first synthesized from morphine by British chemist C. R. Alder Wright. C.R. Wright synthesized heroin by boiling morphine and acetic anhydride over a stove. He tested his creation on dogs and determined that the drugs caused “great prostration, fear, and sleepiness speedily following the administration and a slight tendency to vomiting.”

Source: Heroin (n.d.) In Encyclopædia Britannica.

Drugs: Opium (morphine, heroin, opioids)
Regions: UK (England, Scotland, Wales, Northern Ireland)