1535 CE
First published reference to Tobacco

Gonzalo Fernández de Oviedo’s Historia general de las Indias, which was published in 1535 CE, has the first published reference to tobacco. It condemned tobacco as a “vile vice” but also noted that tobacco was being used by Europeans and African slaves.

Source: Goodman, J. (2005). Tobacco in History and Culture: An Encyclopedia. Detroit: Thomson Gale.

Drugs: Tobacco
Regions: Spain