1511 CE
Coffee was banned as an intoxicant in Mecca

Coffee had made its way to Saudi Arabia by the 15th century, and in 1511 the first Islamic ban on coffee, by the governor of Mecca, shut down all the coffee houses. But his superior, the sultan of Cairo, soon stepped in and overruled the governor.

Source: Parker, S. F., & Austin, M. W. (2011). Coffee-Philosophy for Everyone: Grounds for Debate.

Drugs: Caffeine (coffee, tea, cola, etc.)
Regions: Saudi Arabia
Topics: Prohibition