1927 CE
Merck conducts the first animal testing with MDMA

The first testing of MDMA’s pharmacologic effects on animals was conducted by Merck in 1927. The results of these studies can no longer be found in the Merck archives and remain unknown. No further animal testing with MDMA was done until 1953.

Source: Karch, S. B. (2011). A historical review of MDMA. Open Forensic Science Journal.

Drugs: MDMA (ecstasy)
Regions: USA (United States of America)