1100
The first coffee trees are cultivated on the Arabian peninsula

Around 1100 CE, the first coffee trees are cultivated on the Arabian peninsula. At first, coffee was only used for medicinal and religious purposes, for example by helping religious adepts stay awake during long religious ceremonies, or to suppress hunger during the Ramadan fast.

Source: Elisabetsky, E., & Etkin, N. L. (2009). Ethnopharmacology. Eolss Publishers Company Limited.

Drugs: Caffeine (coffee, tea, cola, etc.)
Regions: Saudi Arabia, Yemen
Topics: Cultivation, production and trade, Cultural factors (social, religious, ritual)